Heidelberg · Industry
The BioMed X Institute in Heidelberg, Germany, is establishing a new research group in the field of
If you hold a PhD and have an outstanding track record or strong interest in the field of Autoimmune Diseases, we invite you to apply with a project proposal for this position in our new, fully funded research group (1 group leader, 2 postdoctoral researchers, 2 research assistants). Each BioMed X project team is sponsored by an industry partner. The sponsor of this call for application is Merck.
Regulatory T cells (Tregs) are crucial for maintaining self-tolerance. Treg alterations occur in autoimmune diseases as well as in age-associated diseases where Treg dysfunction may contribute to chronic inflammation or inflammaging. Tregs in autoimmune disease patients display augmented oxidative signatures and targeting these pathways ameliorates autoimmune disease in preclinical models. Similar metabolic changes have been linked to cellular senescence indicating a link between aging of T cells and autoimmune disease. Metabolic programming defining T cell fate makes this a central node for manipulation with the potential to correct autoimmune diseases and T cell senescence. Due to the pleiotropic roles of T cells beyond Tregs, relevance extends from autoimmune disease to boosting immune responses to infection or vaccination in the elderly, metabolic alteration by caloric restriction and microbiota, as well as transplant tolerance.
Project proposals should focus on the following key challenges:
Original ideas based on preliminary experimental findings are particularly encouraged.
Group leader positions are intended to suit candidates who would like to develop themselves towards a leadership career path either in academia or industry and have typically between four and eight years of relevant postdoctoral research experience
There is flexibility over starting dates, but successful applicants are welcome to take up post starting November 1, 2021.
Please apply online at apply.bio.mx.
As part of the online application procedure, you will be asked to submit:
BioMed X is an independent research institute located on the campus of the University of Heidelberg in Germany. Together with our partners, we identify big biomedical research challenges and provide creative solutions by combining global crowdsourcing with local incubation of the world’s brightest early-career research talents. Each of the highly diverse research teams at BioMed X has access to state-of-the-art research infrastructure and is continuously guided by experienced mentors from academia and industry. At BioMed X, we combine the best of two worlds – academia and industry – and enable breakthrough innovation by making biomedical research more efficient, more agile, and more fun.
BioMed X Institute Im Neuenheimer Feld 515 69120 Heidelberg Germany E-mail: email@example.com Web: https://bio.mx